Invivogen
Menu

HSV-60c control

HSV-60c Naked (control) Unit size Cat. code Docs Qty Price
Control for CDS Ligand HSV60
200 µg
tlrl-hsv60cn
+-
$124.00
HSV-60c/LyoVec™ (control) Unit size Cat. code Docs Qty Price
Control for CDS Ligand HSV60 - LyoVec™ complexed
100 µg
tlrl-hsv60cc
+-
$135.00

CDS Ligand control

HSV-60c (control) is a single-stranded oligonucleotide which, unlike its double-stranded counterpart, HSV-60, is not an IFN-inducer [1].
HSV-60c is also available complexed with the cationic lipid transfection reagent LyoVec™ to facilitate its uptake.

HSV-60 is a 60 bp oligonucleotide containing viral DNA motifs [1]. HSV-60 derives from the herpes simplex virus 1 genome. Transfected HSV-60 was shown to potently induce IFN-β in a TLR-, DAI- and RNA Pol III-independent, but STING-, TBK1- and IRF3-dependent manner. HSV-60 is recognized by IFI16 [1].

 

1. Unterholzner L. et al., 2010. IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol. 11(11):997-1004.

Back to the top

Specifications

Activity: Control for HSV-60 (CDS ligand)

Formulation: naked or complexed with the transfection reagent LyoVec™

Back to the top

Contents

HSV-60c Naked:

  • 200 µg lyophilized HSV-60 Naked
  • 1.5 ml endotoxin-free water

HSV-60c/LyoVec:

  • 100 µg lyophilized HSV-60/LyoVec
    Note: Each vial contains 25 μg of HSV-60c complexed with 50 μg LyoVec™.
  • 10 ml endotoxin-free water

room temperature Product is shipped at room temperature.

store Stored at -20°C.

Back to the top

Customer Service
& Technical Support

CAPTCHA
In order to prevent automated spam submissions, please answer the following question:
9 + 7 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Shopping cart is empty