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HEK-Blue™ MD2-CD14

HEK-Blue™ MD2-CD14 cells stably express the human MD-2 and CD14 genes, as well as an NF-κB/AP1-inducible SEAP (secreted embryonic alkaline phosphatase) reporter gene. MD-2 and CD14 act as co-receptors for TLR4 in the detection of bacterial lipopolysaccharide (LPS).

HEK-Blue™ MD2-CD14 cells do not express TLR4, therefore they can be used to study TLR4 variants or as control cells for HEK-Blue™ hTLR4 cells (which co-express the human TLR4, MD-2 and CD14 genes).

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