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Dexamethasone

Dexamethasone Unit size Cat. code Docs Qty Price
NF-κB Inhibitor - MAPK Inhibitor
100 mg
tlrl-dex
+-
$63.00

NF-κB Inhibitor - MAPK Inhibitor

Dexamethasone is a synthetic glucocorticoid compound with potent anti-inflammatory activities.

It represses a large set of pro-inflammatory genes by blocking NF-κB and MAPK activation during TLR engagement depending on the TLR ligand and whether the adapters MyD88 and TRIF are activated individually or coincidently [1].

 

Reference

1. Bhattacharyya S. et al., 2010. TAK1 targeting by glucocorticoids determines JNK and IkappaB regulation in Toll-like receptor-stimulated macrophages. Blood. 115(10):1921-31.

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Specifications

Working concentration: 100 nM (40 ng/ml)

CAS number: 50-02-2

Synonym: Prednisolone F

Formula: C22H29FO5

Molecular weight: 392.46

Solubility: approximately 25 mg/ml in ethanol

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Contents

  • 100 mg Dexamethasone

room temperature Dexamethasone is shipped at room temperature.

store Store at 4°C.

stable Product is stable for 1 year when properly stored.

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Citations

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