Invivogen
Menu

Anti-hTNF-α-hIgA1

Anti-hTNF-α-hIgA1 Unit size Cat. code Docs Qty Price
100 µg
htnfa-mab6
+-
$291.00

Neutralizing human IgA1 monoclonal antibody against human TNF-α

Anti-hTNF-α-hIgA1 is a neutralizing monoclonal antibody featuring the constant region of the human IgA1 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgA1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M. The neutralizing activity of this human IgA1 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.

Back to the top

Specifications

Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgA1

Back to the top

Contents

100 µg purified anti-hTNFα-hIgA1 antibody, provided azide-free and lyophilized

Back to the top

Customer Service
& Technical Support

CAPTCHA
In order to prevent automated spam submissions, please answer the following question:
12 + 5 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Shopping cart is empty