Antibodies against human or dog CD20

The CD20 antigen is a transmembrane phosphoprotein that is expressed on the surface of  both resting and activated B lymphocytes, but it is lost upon differentiation into plasma cells.

CD20 expression is restricted to B cells and is therefore a useful marker of B-cell lymphomas, as demonstrated in both humans and dogs.

Anti-human CD20 monoclonal antibodies (Rituximab, Ofatumumab, and Obinutuzumab) have been approved by the FDA to treat B-cell non-Hodgkin's lymphoma or chronic lymphocytic leukaemia (CLL).

InvivoGen offers a large choice of anti-human CD20 and anti-dog CD20 monoclonal antibodies, differing in their biological activity.

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