|Anti-β-Gal-hIgA2||Unit size||Cat. code||Docs||Qty||Price|
Isotype control - Human IgA2
Monoclonal human IgA2 antibody against E. coli β-galactosidase
Anti-β-Gal-hIgA2 features the constant region of the human IgA2 isotype and the variable region of Mouse IgG2a Control. Mouse IgG2a Control is a mouse IgG2a monoclonal antibody that targets E. coli β-galactosidase (β-Gal). This antibody was generated by DNA immunization with a plasmid expressing the β-Gal gene in Swiss mice. It can be used as an isotype control for human IgA2 antibodies.
IgA2 is found predominantly in secretory lymphoid tissues, where it plays a critical role in mucosal immunity. IgA2 is highly resistant to enzymatic degradation by bacterial proteases, due to a short hinge region. IgA2 displays no complement-dependent cytotoxicity (CDC) and low antibody-dependent cell-mediated cytotoxicity (ADCC).
Anti-β-Gal-hIgA2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography.
Clonality: Monoclonal antibody
Specificity: Targets cells expressing E. coli β-galactosidase (β-Gal)
Isotype: Human IgA2
Application: Negative control for human IgA2 antibodies
- The absence of binding of Anti-β-Gal-hIgA2 to human cell lines has been controlled using flow cytometry.
- The absence of endotoxins and other bacterial contaminants has been confirmed using HEK-Blue™ TLR4 and HEK-Blue™ TLR2 cells.
200 µg purified anti-β-Gal-IgA2 antibody, provided azide-free and lyophilizedBack to the top