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5-Fluorocytosine (5-FC)

5-Fluorocytosine Unit size Cat. code Docs Qty Price
DNA Synthesis Inhibitor
250 mg
sud-5fc
+-
$124.00

Nucleobase analog for in vitro and in vivo cytotoxicity assays

5-Fluorocytosine is a fluorinated analog of cytosine. 5-FC is approved by the U.S. Food and Drug Administration (FDA) as an antifungal agent used for the treatment of Candida and Cryptococcus.

Lately with the development of gene therapy, 5-FC has been introduced as a prodrug in combination with the cytosine deaminase suicide gene.

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Specifications

CAS number: 2022-85-7

Formula: C4H4FN3O

Molecular weight: 129.1

Working concentration: 200 - 500 μg/ml

Cytosine Deaminase (CD) genes: S. cerevisiae, E.coli

Cytosine Deaminase (CD) fused to uracil phosphoribosyl transferase genes: S. cerevisiaeE.coli

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Contents

  • 250 mg at 10 mg/ml

room temperature 5-FC is shipped at room temperature.

store Store at room temperature in a cool and dark place.

stable 5-FC is stable for one year when properly stored

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Citations

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