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Cytokine & Related Genes
Cytokines are key modulators of the immune system. They are produced mainly by T lymphocytes in response to infectious agents. Some cytokines induce the inflammatory response or stimulate B cells to produce antibodies while others act to offset these effects by downregulation.
Cytokines have been variously named as lymphokines, interleukins and chemokines, based on their presumed function, cell of secretion or target of action. Nowadays, the term interleukin is used largely for designation of newer cytokine molecules. The term chemokine is used for a specific class of cytokines that mediate chemoattraction between cells.
InvivoGen offers a comprehensive list of cytokine genes classified in different families including interleukins and chemokines.
Most cytokine and related genes are provided in the pORF plasmid while some are provided in the pUNO plasmid. pORF plasmids are selectable in bacteria with ampicillin. pUNO plasmids are selectable in bacteria and mammalian cells with blasticidin. The latter allow the generation of stable clones in contrast to pORF plasmids. We can replace the bacterial selection cassette from pORF with a selection cassette that functions both in bacteria and mammalian cells. This selection cassette subcloned from the pSELECT can express the resistance gene of your choice.
Cytokine and related genes families:
- Chemokine Genes
- Chemokine Receptor Genes
- Cytokine Genes
- Cytokine Suppressor Genes
- Immune Receptor Genes
- Interferon Genes
- Interleukin Genes
- Interleukin Receptor Genes
- Interferon Signaling Genes