Selective Antibiotics
InvivoGen is a leader in the production of selective antibiotics. Our state-of-the-art facilities allow us to produce large quantities of high quality antibiotics with purity levels exceeeding 95%. As we manufacture our products, we are able to offer the best prices on the market.
High Quality - As all the products are manufactured by InvivoGen, our antibiotics meet rigorous standards and have passed stringent quality control, which includes verification of potency, purity and stability using microbiological and chromatographic methods. This leads to consistently high quality.
Purity and Stability - All our antibiotics are ultra pure: more than 95% purity for most of them. Their excellent stability allows for exceptional selection and reproducible results.
Ready-to-use Cell Culture Tested Solutions - No weighing needed - Our antibiotics are available in solution filtered to sterility for customer convenience and validated for cell culture usage.
An Excellent Choice of Antibiotics for Selection in Both Mammalian cells and E. coli - Matches up to the antibiotic resistance genes carried by InvivoGen plasmids, built for selection in both mammalian and bacteria cells.
Antibiotic Resistance Genes - All InvivoGen‘s antibiotics are paired with resistance genes that are active both in E. coli and mammalian cells. They are available in their wild-type form in many plasmids provided by InvivoGen, and also as new synthetic alleles devoid of CpGs in pMOD and pCpG plasmids.
Also Available in Fast-Media© - All our selective antibiotics are available in our ready-made microwaveable E. coli media Fast-Media©. The antibiotics are at the appropriate concentration in pre-mixed LB media for selection of E. coli transformants.
Also Available in bulk quantity - inquire for more information.
Specifically inhibits protein synthesis in both prokaryotes and eukaryotes. Resistance to blasticidin is conferred by the blasticidin resistance gene from Bacillus cereus (bsr)
Blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. Resistance to G418 is conferred by the neo gene from Tn5, APH 3‘ II.
Inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome, effective on most bacteria, fungi and higher eukaryotes. Resistance to hygromycin is conferred by the hph gene from E. coli.
Two grades of Hygromycin B are available: Hygromycin B (purity >85%) and HygroGold™ (purity >98%)
Binds and intercalates DNA thus destroying the integrity of the double helix. Phleomycin is active against most bacteria, filamentous fungi, yeast, plant and animal cells. Phleomycin resistance is conferred by the Sh ble gene from Streptoalloteichus hindustanus.
Specifically inhibits peptidyl transfer on both prokaryotic and eukaryotic ribosomes. This antibiotic inhibits the growth of Gram positive bacteria and various animal and insect cells. Resistance to puromycin is conferred by the Pac gene.
Causes cell death by intercalating into DNA and cleaving it. Effective on most aerobic cells and is therefore useful for selection in bacteria, eukaryotic microorganisms, plant and animal cells. Resistance to Zeocin™ is conferred by the Sh ble gene product.