Resveratrol (3,4',5-trihydroxy-trans-stilbene) is a polyphenol found in plants known to possess anti-inflammatory and chemopreventive properties. Resveratrol has been shown to inhibit the expression of proinflammatory markers, including inducible nitric oxide synthase and cyclooxygenase-2 in macrophages and cancer cells [1], block TRIF-dependent signaling pathway of TLR3 and TLR4 [2] and modulate bacterial phagocytosis of macrophages [3]. Resveratrol may exert these diverse effects by suppressing NF-κB activation. Moreover, Resveratrol induces autophagy through its capacity to both inhibit mTOR and activate AMPK.


Working concentration: 10-100 μM (2.3 - 23 μg/ml)
CAS number: 501-36-0
Formula: C14H12O3
Molecular weight:
20 mg/ml in DMSO


• 100 mg Resveratrol provided lyophilized

Resveratrol is shipped at room temperature. Store lyophilized product at -20°C.
Product is stable for 1 year.


1. Lorne E. et al., 2009. Participation of Mammalian Target of Rapamycin Complex 1 in Toll-Like Receptor 2– and 4–Induced Neutrophil Activation and Acute Lung Injury. Am. J. Respir. Cell Mol. Biol. 41: 237 - 245.
2. Bhat, KP, Pezzuto JM., 2002. Cancer chemopreventive activity of resveratrol. Ann. NY Acad. Sci.957:210.-229.
3. Youn HS et al., 2005. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J Immunol. 175(5):3339-46.


Recent articles using InvivoGen Resveratrol



Description NF-κB inhibitor
Cat. Codetlrl-resv
Unit Size100 mg
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