Research Areas
- Innate Immunity
- Toll-Like Receptors
- RIG-I-Like Receptors
- Nod-Like Receptors
- Autophagy and TLRs
- Other Pathogen Sensors
- Inflammasomes
- Danger Signals
- Inhibitors
- Blues™ Reporter Cells
- Lentivirus Production
- Cytokine Signaling
- Immunoglobulin A
- RNA Interference
- Gene Therapy
- Cancer Research
- Cell Culture & Transfection
- Expression Vectors
Literature
Site Update History
Jun 2010: New genes: hATF2, h&mATG14, hCD3D, hCD247 (CD3Z), h&mELK1, hFLK1 (KDR,VEGFR2), h&mFYN, h&mMAP2K1, h&mMAPK8, h&mMAPK12, mSRF, mYES1.
May 2010: New TLR8 ligand: poly(U). New RLR ligand: 5'ppp-dsRNA and control. IgG purification product: protein G / Agarose.
Apr 2010: New genes: pig TLR1,2,5,6,7,9,10. h&mFOS. h&mHMGB2, h&mHMGB3, h&mJUN.
Mar 2010: InvivoGen 2010 Catalog.
New product line: LENTI-Smart™ (lentivirus production kits),
New reporter cell lines : HEK-Blue™ TLR cells, HEK-Blue™ NOD cells, HEK-Blue™ Null cells, B16-Blue™, THP1-Xblue™, HEK-Blue TGF-β, HEK-Blue IL-18/1L-1β, HEK-Blue™ CD40L
New products: TLR2 Ligands, TLR9 Ligands, TLR Inhibitors, Autophagy, Engineered pFUSE, Tagged protein expression
Mar 2010: New genes: h&mCNKSR1, h&mEIF2C1 (AGO1), h&mGABARAPL1, hLSP1, mIL9, hIL19, mIL25, h&mRAB7A, mULK2, hXPO5.
Feb 2010: New genes (autophagy): h&mATG3, h&mATG4A, h&mATG4B, h&mATG5, h&mATG7, hATG10, h&mATG12, mATG16L1, h&mLAMP2, h&mMAP1LC3A, h&mMAP1LC3B, h&mUVRAG, mVPS34 (PIK3C3). New genes (Fc-receptors): h&mFCER1A, h&mFCER1B, h&mFCER1G, hFCER2 (CD32).
Jan 2010: New genes (glycosylation): h&mALG1, h&mALG2, h&mALG3, h&mALG5, hALG6, hALG8, h&mALG9, hALG10, h&mALG12, h&mALG13, h&mALG14, h&mDAD1, h&mB4GALT1, h&mMGAT1, h&mMGAT2, h&mMGAT3, hMGAT4A, hMGAT5A, h&mST6GAL1 (SIAT1).
Dec 2009: New genes: hCD200 (MOX2), h&mFPR1, h&mFPR2, hFPR3, mIL7R, hIL22RA1, mIL22RA2 (IL22BP), mLSP1, mMSK1 (RPS6KA5), h&mRAF1, hS100A12, mSLC15A4, h&mTRIL.
Nov 2009:
- NLRP3 Inflammasome inducer: MSU Crystals and CPPD Crystals,
- NLRP3 Inflammasome inhibitors: Colchicine, Glybenclamide and Z-VAD-FMK
- TLR Signaling Inhibitors: Pepinh-MYD and Pepinh-TRIF
- Reporter cell line: Ramos-Blue™
- Reprogramming genes for iPSC research: KLF4,MYC,OCT4,SOX2 with cell penetrating peptide (CPP) and HA-tag.
Oct 2009: New genes: hDICER1, h&mEIF2C2 (AGO2), h&mERI1 (3'EXO), hMSR1 (CD204), h&mNXF1 (TAP), h&mSIDT1, h&mTARBP2 (TRBP), mXPO5.
Sept 2009: Poly (I:C) Low Mol Weight/LyoVec complex. New genes: h&mBAMBI, hCIITA (MHC2TA), h&mCSF1, mCSF2RA, h&mDIABLO, h&mFGFR4, hFLT3LG, hHDAC5, mIL1R1, mIL1R2, mITCH, mKIT (CD117), hLIN28, hMST1, hSIRPB1, mTANK.
Aug 2009: New genes: h&mAAMP, h&mB2M (FcRn small subunit), hCCR3 (CD193), h&mCD93, mCD200, hCD274, mCLEC9A, hCLEC10A (CD301), mCXCR5 (CD185), h&mDUFFY (DARC,CD234), h&mFCAMR, hFCGR1B (CD64B), h&mFCGRT (FcRn large subunit), h&mIKBKB-HA, h&mIL1F5, mIL1F6, hIL1F7, mIL1F8, h&mIL1RL1 (T1/ST2L), mIL1RL1s (T1/ST2S), mIL6R (CD126), mIL6ST (CD130), h&mLRRFIP2, hSIRPG (CD172G), h&mXCR1.
July 2009: Poly (I:C) Low Mol Weight.
Jun 2009: New genes: mAIM2 (PYHIN4), hAOAH, hCARD11, h&mCD39 (ENTPD1), hCD101 (IGSF2), h&mCD151, h&mCLEC1B, hDectin2 (CLEC6A), mFTL4s7 (VEGFR3), h&mIFI16 (PYHIN2), hIL6R (CD126), mIL8RA (CXCR1,CD181), h&mMIF, mSLAMF2 (CD48).
May 2009: New cell lines: 293XL-hTLR7, 293XL-hTLR8, 293XL-hTLR9.
Apr 2009: New genes: h&mASC-DN, mCD37, hCLEC9A, mCSF2RB (CD131), h&mCTCF, mDectin2 (CLEC6A), hFGF1, hGRP94 (HSP90B1), h&mHDGF, mHGF, mIL23, h&mIL34, h&mIL35, hITGA4 (CD49D), h&mMCM5, hMSK1, h&mMSK2, h&mSLAMF1 (CD150), hSLAMF2 (CD48), h&mSLAMF3 (CD229), h&mSLAMF4 (CD244), h&mSLAMF5 (CD84), h&mSLAMF6, h&mSLAMF7 (CD319), hUHRF1, mVTN (Vitronectin).
Mar 2009: InvivoGen 2009 Catalog.
New products: TLR-IgA Antibodies, TLR Ligands (inflammasome), HEK-Blue™ IL-1β cells, IgA purification, psiRNA ready-made
Jan 2009: New genes: hAIM2 (PYHIN4), h&mBECN1 (Beclin-1), mHMGB1, h&mIL31, mLIN28, h&mMNDA (PYHIN3), hNANOG, h&mOCT4, hPRKCA, hPRKD1, hPTPN11 (SHP2), h&mPTPNS1 (CD172A, SIRPA), mPYHIN1 (IFIX), hSAA1, mSF3B3 (SAP130), h&mSTING (TMEM173,MITA), hTBKBP1 (SINTBAD), h&mUNC93B1, hVTN (Vitronectin).
Dec 2008: New genes: hCLCF1, hCTF1, hFCGR3A, hFCRL2, hFCRL3, mGRP94 (HSP90B1), mIL4R, hIL17C, hIL18R1, h&mIL20, hJAK1, hJAK2, h&mKLF4, h&mMINCLE (CLEC4E), h&mMUL1 (MULAN), mNANOG, hPECAM1 (CD31), h&mSOX2, mSYK, mTNFRSF11A, mTNFRSF13C, h&mTNFRSF18, h&mTREX1, hTSLP, mUHRF1.
Nov 2008: R848
Sept 2008:
- Dectin-1 ligands: Depleted Zymosan, HKSC, HKCA.
- New TLR7/8 agonist: ORN 02, ORN 06.
- New genes: hssHMGB1, h&mssS100A8, h&mssS100A9.
- New ready-made psiRNA: h&mAGER, h&mKRAS.
Aug 2008: New genes : h&mAXL, mDDX3X, mFASL (TNFSF6,CD178), mOX40 (TNFSF4,CD252), mOX40L (TNFRSF4,CD134), h&mPTPN6 (SHP1), mTNFRSF1A (TNFR1,CD120a), mTNFRSF1B (TNFR2,CD120b), hTNFRSF10A (TRAILR1,CD261), mTNFRSF10B (TRAILR2,CD262), hTNFRSF10D (TRAILR4,CD264), h&mTNFRSF14 (LIGHTR), h&mTNFSF15, mTNIP3 (ABIN3), mTWEAK (TNFSF12), h&mTWEAKR (TNFRSF12A,CD266).
Jun 2008: New genes : mASC, h&mBDNF, h&mBMP7, hBTLA (CD272), mCCL27, h&mCD147 (BSG), hCSF3R (CD114), hCTCFL (BORIS), hEGFR, hFCGR3B, hIGF1R, hIL26, hIL28A, h&mIRS1, h&mITGB1 (CD29), mJAK2, hLRP6, mOTUD5 (DUBA), mPANX1, hPDGFRA (CD140), h&mSPP1 (Osteopontin), hSYK, hTANK, mTNFAIP6, hTNIP1 (ABIN1), hTNIP3 (ABIN3), mTSLP, h&mTYRO3.
May 2008:
- DNA vaccine booster: pBOOST3-mTBK1.
- New TLR9 suppressive ODN: G-ODN.
- New TLR-signaling inhibitors: AG490, Celastrol, H-89, SP600125, Wortmannin.
- New PromTest plasmids: pDRIVE5-GFP series
- pFUSE Constant Light Lambda , pFUSE2 Constant Light Kappa & Lambda.
Mar 2008: InvivoGen 2008 Catalog.
- Innate Immunity: NLR Expressing Cell Lines, NLR primers, NOD agonist kit, new TLR Expressing Cell Lines, TLR7/8 ligand: Poly(dT), new ODNs control, FITC ODN
- Cytokine Signaling: Recombinant Cytokine IL-1β
- IgA antibodies : IL-1β-IgA, Protein L / Agarose
- RNA Interference: new ready-made psiRNA
- Cloning Vectors: pFUSE-mIgG2b-Fc1, pFUSE-mIgG2b-Fc2, pINFUSE: Fc regions with introns, control pFUSE (pFUSE-SEAP-Fc), pFUSE Constant Light Kappa, pFUSE Constant Heavy.
- Cellular Promoters: PromTest™
- Cancer Research: Celastrol, Triptolide, new geldanamycin analogue (17-NHS-ALA-GA)
- New packaging: Fast Media, LyoComp, ODNs
Mar 2008: New genes : h&mBCL3, h&mBTK, hCARD6 (CINCIN1), h&mDAK, hEEF2, h&mEGF, h&mEPOR, h&mGH1, mGHR, mIL17B, mIL17C, hIL17RC, h&mMAP3K3 (MEKK3), mMAP3K14 (NIK), h&mMDK, mNAIP5 (BIRC1E), hNFKBIE, h&mNOD9 (NLRX1), hPANX1, h&mPPP3CA, h&mPTN, h&mRNF125 (TRAC1), h&mS100A8, h&mS100A9, hSUGT1b, mTNFAIP3 (A20), hTNFRSF13B (CD267, TACI), mTNIP1, h&mTNIP2, hTPOR (MPL, CD110), hXBP1, h&mZBP1 (DAI).
Feb 2008: New genes : hCEBPB, hCITED2, hCOP1a (Pseudo-ICE), hEG1, hHIF1A, hICEBERG (ICBR), hINCA, h&mLKLF, hLRRC32 (GARP), hMEFV (PYRIN), h&mMYC, h&mSP1, hSPI1 (PU.1), h&mSTAT3, h&mSTAT4, h&mSTA5A, hSTAT5B, h&mSTAT6. New product: HEK-Blue™ TNF-α/IL-1β Cells.
Jan 2008: Neutralizing IgA antibodies against human TLR2, TLR4, TLR5, IFNα, IL-4, IL-6, IL-13, TNFα.
Dec 2007: New genes : hSMAD2, hSMAD3, hSMAD4, hSMAD6, hSMAD7.
Nov 2007: New genes : h&mAGER (RAGE), mAOAH, h&mBAFF (TALL1, TNFSF13B) , hBAFFR (TNFRSF13C), h&mBMP4, hCARD9, h&mCD153 (TNFSF8), hCNTF, hCNTFR, hDECTIN1a, mFGF3, mFGF10, hFGFR2 (CD332), hHDAC11, mHGFAC, h&mIFNGR1, h&mIFNGR2, hIL1R2, hIL12RB2, h&mKRT8, hMAP3K14 (NIK), hMYST1a, hNALP11, mPDGFRA (CD140A), mPRKCA (PKCA), h&mSCGF (CLEC11A), hSIRT1, hTGFA, h&mTGFB3, hTGFBR1, hTGFBR2, h&mTRAF1, h&mTRAF2, mTRAF3, h&mTRAF4, h&mTRAF5, hVEGFD (FIGF).
Oct 2007: New genes : hCCL28, h&mCD3E, mCD19, h&mCD44, hCD45, h&mCTLA4 (CD152), mCXCL16, h&mIL15RA, mIL17A, mIL23R, hIL25b, hIL28, h&mLAG3 (CD223), mMIP2A (CXCL2), hTNFRSF10C (CD263), mTNFRSF13B (CD267), h&mTNFRSF17 (CD269). Gene search-engine added, for easier access to ORFs provided by InvivoGen.
Sept 2007: New genes : hBPI, hCCR5, h&mCCR9, hCCR10, hCCRL2, hCXCR5 (BRL1), hCXCR6, hHSP10 (HSPE1), mMDA5 (IFIH1), hNFkBp52 (NFKB2), hNFkBp100, h&mNFKBIA, hNFKBIB, mNFKBIE, h&mPRAT4A, mPRAT4B, h&mPTX3, h&mRELB, h&mSLPI, h&mTRIM25.
Jun 2007: New genes : h&mCCR1, h&mCCR2, mCCR3, h&mCCR4, h&mCCR6, h&mCCR7, h&mCCR8, h&mCCBP2, mCXCR6, h&mCXCR7.
May 2007: TLR4 Reporter Cell Lines (MEF & HEK293). New TLR4 ligands (LPS-RS, MPLAs, LPS-EB). New NOD1 ligands (iE-DAP, Tri-DAP, C12-iE-DAP, M-Tri-DAP).
Mar 2007: New genes : h&mBCL10, hCD1B, hCD1C, hCD1D, h&mCD2, h&mCD7, hCD19, h&mCD82, hCENTB1, hCSF2RB (CD131,IL3RB,IL5RB), mIL2RA (CD25), hIL4R (CD124), hIL6ST (CD130), hIL7R, h&mIL11RA, hIL17D, hIL17RB, hIL17RD, mIL24, mIL30 (IL27), h&mLGP2, hLIFR (CD118), hLIFR(soluble), hNALP12, hNIBP (T1), hOX40 (TNFRSF4, CD134), hSHIP1 (INPP5D), h&mSIKE, mTRAFD1 (FLN29), h&mUBP43 (USP18).
Feb 2007: InvivoGen 2007 Catalog.
- Cytokine Signaling: Cytokine Sensor Cells, Recombinant cytokines, IFNr qRT primers
- TLRs & Innate Immunity: TLR-GFP fusions, TLR7/8 agonists, THP1-Blue Clones
- Cell culture: Plasmocure
- RNA Interference: Pre-complexed psiRNAs, pCpGsiRNA-DUO
- Cancer Research: New geldanamycin analogues (17AAGH2, 17DMAGH2)