Ready-made psiRNA

Plasmids Expressing Functional shRNAs

Ready-mande psiRNA-h7SK GFPZeo backboneReady-made psiRNA is a family of plasmids expressing a growing list of shRNAs which functionality has been described in the literature or validated in house. Ready-made psiRNA plasmids eliminate the need to design and clone several siRNA sequences before identifying an effective one. They express shRNAs that silence the expression of a target gene by >70%.

Ready-made psiRNAs are psiRNA-h7SKGFPzeo-derived plasmids. They feature the human 7SK RNA Pol III promoter that generates high amounts of short hairpin RNAs and the GFP::Zeo fusion gene which confers both reporter and antibiotic resistance activities. Therefore, ready-made psiRNAs are very useful to monitor transfection efficiency, standardize gene silencing efficiency and select clones that stably express a validated shRNA.

Ready-made psiRNA plasmids are available alone or in a kit.

Ready-made psiRNA

TLR shRNAsshort hairpin RNAs that target Toll-Like Receptors genes
TLR-Related shRNAsshort hairpin RNAs that target genes encoding proteins involved in TLR signaling pathways
NLR shRNAsshort hairpin RNAs that target NOD-Like Receptor and NLR-related genes
RLR shRNAsshort hairpin RNAs that target the RIG-I-like receptor and RLR-related genes
CLR shRNAsshort hairpin RNAs that target various genes encoding receptors involved in pathogen recognition
CDS shRNAsshort hairpin RNAs that target the cytosolic dsDNA Sensor (CDS) and CDS-related genes
DAMPs shRNAsshort hairpin RNAs that target the damage associated molecular patterns (DAMPs) related genes
Autophagy-related shRNAsshort hairpin RNAs that target genes encoding proteins involved in autophagy
Inhibitors of Signaling shRNAsshort hairpin RNAs that target various inhibitors of signaling genes
Signaling effectors shRNAsshort hairpin RNAs that target genes encoding proteins involved in signaling
Cytokine & Related shRNAsshort hairpin RNAs that target cytokine production and signaling pathways genes
Remodeling shRNAsshort hairpin RNAs that target genes encoding proteins involved in chromatin-remodeling
Disease-related shRNAsshort hairpin RNAs that target genes encoding proteins involved in human diseases
Reporter shRNAsshort hairpin RNAs that target a variety of reporter genes
Miscellaneous shRNAsshort hairpin RNAs that target various genes
All InvivoGen's ORFs shRNAshort hairpin RNAs that target the late SV40 polyadenylation signal (polyA)
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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