pFUSE-hIgG2-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG2 heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. Human IgG2 dispays low ADCC and CDC.

hIgG2-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted


Isotype: Human IgG2
Effector Activities: ADCC+/-, CDC +
Protein A binding: ++++
Protein G binding: ++++

Both plasmids are selectable with Zeocin™.


• 20 μg of lyophilized DNA
• 4 pouches of E. coli Fast-Media® Zeo (2 TB and 2 Agar)


Recent articles using InvivoGen pFUSE-hIgG2-Fc



Cat. Codepfuse-hfc1
Unit Size20 µg
Price For price or distributor address,
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Cat. Codepfuse-hfc2
Unit Size20 µg
Price For price or distributor address,
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