Peptide M / Agarose
Peptide M is a 50 aa synthetic peptide derived from a streptococcal M protein containing an additional C-terminal cysteine residue. Peptide M binds monomeric and dimeric human IgA of both subclasses (IgA1 and IgA2) with high specificity and affinity. It also binds bovine IgA but not murine IgA. Peptide M binding occurs at a site in IgA-Fc conserved in human IgA1 and IgA2 and bovine IgA but not in mouse IgA. Peptide M can be used for single-step affinity purification of IgA and for specific detection of antigen-bound IgA.
Specifications
Binding capacity: 4 - 6 mg human IgA per ml of gel
Documents
Contents
Peptide M / Agarose is available in two quantities:
• gel-pdm-2: 2 ml Peptide M / Agarose provided as a 50% v/v gel slurry in PBS 20% v/v ethanol (total volume 4 ml)
• gel-pdm-5: 5 ml Peptide M / Agarose provided as a 50% v/v gel slurry in PBS 20% v/v ethanol (total volume 10 ml)
Ref.
1. Sandin C. et al., 2002. Isolation and detection of human IgA using a streptococcal IgA binding peptide. J Immunol. 169(3):1357-64.
ORDERING
Peptide M / Agarose
| Cat. Code | gel-pdm-2 |
|---|---|
| Unit Size | 2 ml |
| Price | For price or distributor address, please select your country |
Peptide M / Agarose
| Cat. Code | gel-pdm-5 |
|---|---|
| Unit Size | 5 ml |
| Price | For price or distributor address, please select your country |
