FITC labeled CpG oligonucleotide - Human TLR9 ligand

CpG  ODNs are synthetic oligonucleotides that contain unmethylated CpG  dinucleotides in particular sequence contexts (CpG motifs). These CpG  motifs are present at a 20-fold greater frequency in bacterial DNA  compared to mammalian DNA. They have been shown to induce a coordinated  set of immune responses based on the activation of immune cells  primarily involved in the recognition of these molecules.

ODN  2216 FITC is a A-class CpG ODN with a preference for human TLR9. ODN 2216 FITC can  be used to evaluate CpG ODN cellular uptake and localization by  confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm)  or flow cytometry.


Specificity: human TLR9 agonist

Working concentration: 1-5 μM

ODN 2216 sequence
5’-ggGGGACGA:TCGTCgggggg-3’ (20 mer)
Note: Bases in capital letters are phosphodiester and those in lower case are phosphorothioate.

Spectral Properties of FITC
Excitation λ max: 495 nm
Emission λ max: 520 nm


• 50 μg (7 nmol) lyophilized ODN 2216 labeled with FITC at the 3’ end
• 1 ml sterile endotoxin-free water

ODN 2216 FITC is shipped at room temperature and should be stored at -20°C. Protect from light. Upon resuspension, ODN 2216 FITC should be aliquoted and stored at -20°C. Resuspended product is stable 6 months when properly stored. Avoid repeated freeze-thaw cycles.



Description Class A - FITC-labeled ODN 2216
Cat. Codetlrl-2216f
Unit Size50 µg
Price For price or distributor address,
please select your country
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
Copyrights © 2011-2016 InvivoGen. All Rights Reserved. Reproduction of any materials from this site is strictly forbidden without permission for commercial use. Nonprofit use for non-commercial research and educational purposes is permitted, citation should include the URL "www.invivogen.com".