PRR Ligands

InvivoGen provides an extensive set of tools to study the innate immune system, including a comprehensive collection of pathogen-associated molecular patterns (PAMPs).

PAMPS are recognized by pattern recognition receptors (PRRs).

Five families of PRRs have been shown to initiate pro-inflammatory signaling pathways:

• Toll-like receptors (TLRs)
• NOD-like receptors (NLRs)
• RIG-I-like receptors (RLRs)
• C-type lectin receptors (CLRs)
• cGAS and other cytosolic DNA sensors (CDSs)

Also, some NLRs are involved in the formation of pro-inflammatory complexes called inflammasomes.

We also provide labeled ligands to activate or study these receptors, and we offer diverse NF-κB and NFAT activators.