LENTI-Smart™ OSKM
For the Generation of iPS Cells
Induced pluripotent stem (iPS) cells are generated from differentiated somatic cells overexpressing a set of specific transcription factors called reprogramming factors. Typically four reprogramming factors are chosen, Oct4, Sox2, Klf4 and c-Myc (OSKM), which are introduced into the target cells through genetic transduction using retroviral or lentiviral vectors.
To facilitate the generation of iPS cells, InvivoGen has developed LENTI-Smart™ OSKM for the production of lentiviral vectors expressing the human or murine OSKM reprogramming genes. LENTI-Smart™ OSKM comprises the complexing lyophilizate, formed by the packaging plasmids and the transfection reagent, and the lentiviral plasmid expressing the OSKM genes of human or mouse origin.
Two LENTI-Smart™ OSKM kits are available allowing the generation of integrating (LENTI-Smart™ INT OSKM) or non-integrating (LENTI-Smart™ INT OSKM) lentiviral vectors.
LENTI-Smart™ OSKM Products
Integrative |
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Non-integrative |
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