Immunomodulators

InvivoGen offers a wide selection of immunomodulators of the signaling pathways initiated by pattern recognition receptors (PRRs).

These molecules intervene in the different steps of PRR activation and signaling cascade, including ligand binding, interaction with adapters and activation of MAP kinases and NF-κB. Immunomodulators include a large variety of compounds.

Immunomodulators

Small molecules and peptides

Innate Immunity Signaling Inhibitors Innate Immunity Signaling Inhibitors
NF-κB & MAPK Activation Inhibitors Inhibitors of NF-κB and MAP kinase activation
mTOR & Calcineurin Signaling Inhibitors Inhibitors of mTOR and Calcineurin Signaling
JAK/STAT Activation Inhibitors Inhibitors of JAK/STAT activation
Antimicrobial peptide LL-37: Antimicrobial peptide

Short hairpin RNAs

PRR and related shRNAs shRNAs targeting PRR and related genes

Antibodies

Antibodies for Neutralization Antibodies for PRR Neutralization and flow cytometry

Ligands

TLR Antagonists TLR4 and TLR9 ligands that block the signaling cascade
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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