HEK-Blue™ MD2-CD14

HEK-Blue™ MD2-CD14 cells stably express the human MD-2 and CD14 genes, as well as an NF-κB/AP1-inducible SEAP (secreted embryonic alkaline phosphatase) reporter gene. MD-2 and CD14 act as co-receptors for TLR4 in the detection of bacterial lipopolysaccharide (LPS).

HEK-Blue™ MD2-CD14 cells do not express TLR4, therefore they can be used to study TLR4 variants or as control cells for HEK-Blue™ hTLR4 cells (which co-express the human TLR4, MD-2 and CD14 genes).

HEK-Blue™ hMD2-CD14Human MD2-CD14 / NF-κB / SEAP reporter HEK293 cells3-7 x 10e6 cells
HEK-Blue™ Null2 cellsNF-kappaB / SEAP parental cell line3-7 x 10e6 cells
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Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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