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Zeocin™

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Zeocin™

InvivoGen is the sole worldwide producer of Zeocin™, a copper-chelated glycopeptide antibiotic produced by Streptomyces CL990.

Zeocin™ causes cell death by intercalating into DNA and cleaving it. This antibiotic is effective on most aerobic cells and is therefore useful for selection in bacteria, eukaryotic microorganisms, plant and animal cells.
Resistance to Zeocin™ is conferred by the Sh ble gene product which inactivates Zeocin™ by binding to the antibiotic.

Zeocin™ is used at a concentration of 50-300 µg/ml for selection in mammalian cells and 25 µg/ml for bacterial selection.

Technical information about Zeocin™.

Empirical formula: C₅₅H₈₅O₂₁N₂₀S₂Cu - HCl
Molecular weight: 1525

Bulk quantities available at highly discounted prices : Contact info@invivogen.com

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Cloning vectors using Zeocin™

Invivogen offers several selection vectors using Zeocin™ as selection antibiotic: - pSELECT-zeo-mcs, pSELECT-gfpzeo-mcs, pSELECT-zeo-LacZ, pSELECT-gfpzeo-LacZ : pSELECT plasmids offer all the features necessary to express a gene of interest at high levels in a large number of cell types.
- pMONO-zeo-mcs, pMONO-zeo-gfp : pMONO plasmids are specifically designed for strong and constitutive expression of a gene of interest in a wide variety of cell lines.
- psiRNA-h7SK G1 Zeo, psiRNA-h7SK G1 GFPzeo, psiRNA-DUO : psiRNA-h7SK offer all the features necessary to express shRNA under the human 7SK RNA polymerase III promoter.
- pCpG-free: pCpGfree is an expression vectors completely devoid of CpG dinucleotides that is selectable in mammalian cells

Contents and Storage

Zeocin™ is provided as a blue solution at 100 mg/ml.
Zeocin™ is shipped at room temperature and upon receipt should be stored at -20°C. Zeocin™ is stable for at least 1 year at -20°C.

Product	TDS	MSDS	Qty	Cat. Code	Price
Zeocin™	PDF	PDF	1 g	ant-zn-1	check
Zeocin™	PDF	PDF	5 g (25 x 2 ml)	ant-zn-5	check
Zeocin™	PDF	PDF	5 g (50 ml bottle)	ant-zn-5b	check
Zeocin™	PDF	PDF	1 g (powder)	ant-zn-1p	check
Zeocin™	PDF	PDF	5 g (powder)	ant-zn-5p	check

Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.

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