HEK-Blue™ Cytokine Cells
Blue™ Cytokine Reporter Cells is an expanding family of engineered HEK293 cell lines designed to provide a simple, rapid and reliable method to monitor the activation of signaling pathways induced by key cytokines. They allow to detect these biologically active cytokines. HEK-Blue™ Cells express an inducible secreted embryonic alkaline phosphatase (SEAP) reporter gene. This SEAP reporter gene is under the control of specific promoters that are selectively activated by cytokines. Therefore, in the presence of cytokines, the pathway is activated inducing the production of SEAP. The amount of SEAP secreted in the cell supernatant can be measured spectrophotometrically with QUANTI-Blue™.
HEK-Blue™ Cytokine Cells Products
JAK/STAT Pathway |
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NF-κB Pathway |
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Smad Pathway |
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CD40 Pathway |
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