CDS Ligands

Double-stranded DNA (dsDNA) is a potent inducer of type I interferons. It is recognized by different cytosolic dsDNA sensors (CDSs), such as DAI and LRRFIP1. InvivoGen provides AT-rich B-form dsDNA and GC-rich Z-form dsDNA, known to activate these CDSs.

CDS Ligands Products

Poly(dA:dT) Naked RIG-I Agonist - CDS Agonist - AIM2 Inflammasome Inducer 200 µg
1 mg
Poly(dA:dT)/Lyovec™ RIG-I Agonist - CDS Agonist - AIM2 Inflammasome Inducer 100 µg
Poly(dG:dC) Naked RIG-I Agonist - CDS Agonist 200 µg
Poly(dG:dC)/Lyovec™ RIG-I Agonist - CDS Agonist 100 µg
Disclaimer: Our products are provided for research purpose only. Commercial applications may require licensing from third parties.
Note that the sequence of available ORFs provided by InvivoGen can differ from a given reference Genbank record due to genetic variations and/or alternative splicing. Customers should verify that the version of a gene sold by InvivoGen is suitable for the customer needs.
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