Our Products
Cancer Research
Anti-Tumor Genes
InvivoGen provides a list of genes with potential anti-tumor activity: Angiostatic genes, Apoptotic genes, Cytotoxic/suicide genes, Tumor Antigen genes and Tumor Suppressor genes
Theses genes can be used to analyze their function or to eliminate tumors in cancer gene therapy studies.
To target transgene expression in tumors, InvivoGen offers a selection of native tumor-specific promoters and composite tumor-specific promoters, active either in a wide range of tumors or in a specific tissue and tumor.
Anticancer Agents - Terpenoids
Terpenoids are a large and diverse class of naturally-occurring organic chemicals found in all classes of living organisms. They are currently under investigation by numerous groups for anti-tumor, anti-inflammatory and other therapeutic properties.
Anticancer Agents - Geldanamycin & Analogues
Geldanamycin (GA), a benzoquinone ansamycin antibiotic inhibits the proliferation of cancer cells and shows anticancer activity in experimental animals. Numerous GA analogues have been synthesized which differ only in their 17-substituent that have completed phase I and are currently entering phase II clinical trials.
InvivoGen provides Geldanamycin and its more promising analogues as well as other derivatives.
Anticancer Agents - Epigenetic Inhibitors
InvivoGen provides two such inhibitors: 5Aza-dCyd, inhibitor of DNA methyltransferases (DNMTs) and Trichostatin A, inhibitor of histone deacetylases (HDACs). Both inhibitors have been demonstrated to be promising anticancer agents used either separately or in combination.