Blasticidin S
Blasticidin S is a peptidyl nucleoside antibiotic isolated from Streptomyces griseochromogenes. It specifically inhibits protein synthesis in both prokaryotes and eukaryotes by interfering with the peptide bound formation in the ribosomal machinery.
Resistance to blasticidin is conferred by the blasticidin resistance gene from Bacillus cereus (bsr) which codes for blasticidin deaminase.
Typically, bacteria are sensitive to blasticidin concentrations of 25-100 µg/ml, and mammalian cells to 1-10 µg/ml.
Specifications
Working concentration:
- 25-100 µg/ml in bacteria
- 1-10 µg/ml in mammalian cells
CAS number: 3513-03-9
Purity: >95%
Molecular weight: 458.9
Formula: C17H26N8O5, 1 HCl
Documents
- TDS Blasticidin S (solution) : 500 mg (25 x 2 ml) (ant-bl-5) , 100 mg (5 x 2 ml) (ant-bl-1) , 500 mg (50 ml bottle) (ant-bl-5b)
- TDS Blasticidin S (powder) : 1 g (ant-bl-10p)
- MSDS Blasticidin S (solution) : 500 mg (25 x 2 ml) (ant-bl-5) , 100 mg (5 x 2 ml) (ant-bl-1) , 500 mg (50 ml bottle) (ant-bl-5b)
- MSDS Blasticidin S (powder) : 1 g (ant-bl-10p)
Contents
Blasticidin S hydrochloride is supplied as a colorless solution in HEPES buffer or as a powder in different formats:
- 5 x 2ml at 10 mg/ml (100 mg)
- 25 x 2ml at 10 mg/ml (500 mg)
- 1 x 50ml at 10 mg/ml (500 mg)
- 1 g (powder)
Details
Ref.
- PEREZ-GONZALEZ J.A. et al. (1990). Gene.86: 129-134.
- IZUMIM. et al. (1991). Exp.Cell Res.197: 229-233.
- ITAYA M. et al. (1990). J.Biochem. 107: 799-801.
- KIMURA M. et al. (1994). Mol. Gen. Genet. 242: 121-129.
- KIMURA M. et al. (1994). Biochim.Biophys.Acta.1219:653-659
ORDERING
Blasticidin S (solution)
| Cat. Code | ant-bl-1 |
|---|---|
| Unit Size | 100 mg (5 x 2 ml) |
| Price | For price or distributor address, please select your country |
Blasticidin S (solution)
| Cat. Code | ant-bl-5b |
|---|---|
| Unit Size | 500 mg (50 ml bottle) |
| Price | For price or distributor address, please select your country |
Blasticidin S (solution)
| Cat. Code | ant-bl-5 |
|---|---|
| Unit Size | 500 mg (25 x 2 ml) |
| Price | For price or distributor address, please select your country |
Blasticidin S (powder)
| Cat. Code | ant-bl-10p |
|---|---|
| Unit Size | 1 g |
| Price | For price or distributor address, please select your country |
