5-Fluorocytosine (5-FC)

Nucleobase analog for in vitro and in vivo cytotoxicity assays

5-Fluorocytosine is a fluorinated analog of cytosine. 5-FC is approved by the U.S. Food and Drug Administration (FDA) as an antifungal agent used for the treatment of Candida and Cryptococcus. Lately with the development of gene therapy, 5-FC has been introduced as a prodrug in combination with the cytosine deaminase suicide gene.


CAS number: 2022-85-7
Formula: C4H4FN3O
Molecular weight:
Working concentration:
200 - 500 μg/ml

Cytosine Deaminase (CD) genes:
S. cerevisiae, E.coli

Cytosine Deaminase (CD) fused to uracil phosphoribosyl transferase genes:
S. cerevisiaeE.coli


- 250 mg at 10 mg/ml


Recent articles using InvivoGen 5-Fluorocytosine (5-FC)



Description DNA Synthesis Inhibitor
Cat. Codesud-5fc
Unit Size250 mg
Price For price or distributor address,
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